Optimising Knee Therapies

Date: January 9, 2019 @ 9:00 AM


Researchers from the University of Leeds will be presenting the latest research from the EPSRC Programme Grant, alongside invited keynote speakers from other academic and clinical centres in Europe and the USA. Although the focus will be on the knee, the meeting will be of interest to those involved in musculoskeletal devices and preclinical testing.

The event will take place at Weetwood Hall and the agenda is as below. There is free parking onsite and regular bus links to Leeds city centre.

Please register via the EventBrite link.



09:30  Welcome and Introduction – Ruth Wilcox

Session 1

09:50   Aiqin Liu  Development of an in vitro experimental model to investigate the contact mechanics of the natural knee

10:05  Robert Cooper  Approaches to subject-specific finite element knee models

10:20  Anthony Herbert  The strain rate dependent and dynamic mechanical properties of a decellularised biological scaffold for ACL replacement


11:00  Marlène Mengoni  Characterization of osteochondral grafts and their interactions with their host environment

11:20  Hazel Fermor  Decellularised osteochondral scaffolds: Proof of concept

Keynote 1

11:40  Professor Ilse Jonkers (KU Leuven)
To load or overload: Steps to unravel the million-dollar OA-question

12:20  Poster Pitches

12:45  LUNCH

Keynote 2

13:45  Professor Gerard Ateshian (Columbia University)
Cartilage Tissue Engineering versus Osteochondral Allografts: Challenges and Strategies for Viable Long-Term

Session 2

14:15  Jennifer Edwards  Development and testing of a novel sterilisation process for use with decellularised human bone-tendon-bone grafts

14:35  Bright Dube  Determinants of osteoarthritis 3D bone shape and its change in the three knee bones: a latent growth modelling approach on 37 583 MR images from the Osteoarthritis Initiative

14:55  Louise Jennings (Leeds) & Virginie Sottile (University of Nottingham)  Preclinical functional performance assessment of a new bio-inspired non-delaminating osteochondral construct


15:45  Panel Discussion / Debate

16:30  Close Meeting

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